- Steve Wandzniak makes a return in this short who only appeared in the canon series episode, "Return of the L.O.S.E.R.S.".
- After Cosmo combined science liquids together, Mr. and Mrs. Turner got blown out of their house the same way Poof blew the Turner's out of the house in "Planet Poof".
- When Cosmo's voice got lower when turned smart, Neptunia claims his smart voice sounds like a used car salesman, a reference to Cosmo's old voice in the original series' shorts.
- Regular Show - This short is a bit similar to the Regular Show episode, "More Smarter".
- The Simpsons - This short has a similar title to the Simpsons episode "Bart the Genius".
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